Stressing over a surprise drug test or are you trying to find peace of mind before dosing yourself with psilocybin? Well, don't I have some lovely news for you psilocybin is generally not included in most drug testing panels! However, this does not mean that psilocybin is not detectable as an extended drug testing panel may include psilocybin. Psilocybin is usually out of the system within 24 hours for most people. Have a safe trip!